SCHEMBL31335112

SCHEMBL31335112

C[C@H](Oc1cc(-c2cnn(C(C)(C)C)c2)cc2ncccc12)[C@@H]1CN(C(=O)OC(C)(C)C)CCO1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 20/20 0.52
▸ FLT3 P36888 5/20 0.46
▸ AURKB Q96GD4 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30613604 1.00 SYK (0.52) SYKFLT3AURKB
SCHEMBL31335120 1.00 SYK (0.52) SYKFLT3AURKB
SCHEMBL30613640 1.00 SYK (0.52) SYKFLT3AURKB
SCHEMBL30613606 0.86 SYK (0.46) SYKFLT3AURKB
SCHEMBL31335340 0.84 SYK (0.50) SYKFLT3AURKB
SCHEMBL30613676 0.84 SYK (0.50) SYKFLT3AURKB
SCHEMBL31335177 0.80 SYK (0.57) SYKFLT3AURKB
SCHEMBL31676306 0.80 SYK (0.57) SYKFLT3AURKB
SCHEMBL30613621 0.71 EPHA2 (0.46) SYK
SCHEMBL30613620 0.71 EPHA2 (0.46) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119325474-A Spleen tyrosine kinase inhibitors 尤尼奎斯特公司 2025-01-17 — — CN disclosed
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