Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141411 | 0.98 | CYP2A6 (0.41) | CYP2A6HTR1AHTR7TLR4TLR2 | |
| SCHEMBL15606465 | 0.91 | CYP2A6 (0.40) | CYP2A6HTR1AHTR7TLR4TLR2 | |
| SCHEMBL5106134 | 0.89 | CYP2A6 (0.43) | CYP2A6LMNAKDM4ECCR1CCR5 | |
| SCHEMBL16484524 | 0.89 | CYP2A6 (0.46) | CYP2A6HTR1AHTR7TLR4TLR2 | |
| SCHEMBL30109153 | 0.89 | CYP2A6 (0.46) | CYP2A6HTR1AHTR7TLR4TLR2 | |
| SCHEMBL5115970 | 0.89 | CYP2A6 (0.46) | CYP2A6HTR1AHTR7TLR4TLR2 | |
| SCHEMBL28432843 | 0.88 | GRM5 (0.43) | CYP2A6HTR1AHTR7TLR4TLR2 | |
| SCHEMBL5102763 | 0.87 | CYP2A6 (0.44) | CYP2A6HTR1AHTR7TLR4TLR2 | |
| SCHEMBL6692821 | 0.86 | GRM5 (0.37) | CYP2A6HTR1AHTR7TLR4TLR2 | |
| SCHEMBL26849314 | 0.85 | CYP2A6 (0.46) | CYP2A6HTR1AHTR7TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1491074-B1 | PHOSPHORESCENT DENDRIMERS FOR USE IN LIGHT-EMITTING DEVICES | UNIV OXFORD INNOVATION LTD (GB) | 2017-07-26 | — | — | EP | disclosed |
| US-7641986-B2 | Having at least one layer that contains phosphorescent organometallic dendrimer with metal cation and two or more coordinating groups as part of core and wherein at least two of coordinating groups each have dendron attached, at least one of which comprises nitrogen atom which forms part of aromatic ring | ISIS INNOVATION LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-20050116622-A1 | Phosphorescent dendrimers for use in light-emitting devices | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2005-06-02 | — | — | US | disclosed |
| EP-1491074-A1 | PHOSPHORESCENT DENDRIMERS FOR USE IN LIGHT-EMITTING DEVICES | ISIS INNOVATION LIMITED (GB) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003079736-A1 | PHOSPHORESCENT DENDRIMERS FOR USE IN LIGHT-EMITTING DEVICES | ISIS INNOVATION LIMITED (GB) | 2003-09-25 | — | — | WO | disclosed |