Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26125149 | 1.00 | HDAC6 (0.52) | HDAC6HDAC1KDM4ENPC1ALDH1A1 | |
| SCHEMBL26530409 | 0.91 | KDM4E (0.46) | HDAC6HDAC1KDM4ENPC1ALDH1A1 | |
| SCHEMBL26528722 | 0.89 | HDAC6 (0.59) | HDAC6HDAC1NPC1ALDH1A1RAB9A | |
| SCHEMBL26530031 | 0.88 | HDAC6 (0.50) | HDAC6HDAC1 | |
| SCHEMBL26124131 | 0.88 | HDAC6 (0.52) | HDAC6 | |
| SCHEMBL30574361 | 0.88 | HDAC6 (0.52) | HDAC6 | |
| SCHEMBL31336078 | 0.87 | HDAC6 (0.59) | HDAC6HDAC1 | |
| SCHEMBL26128261 | 0.87 | HDAC6 (0.59) | HDAC6HDAC1 | |
| SCHEMBL26124741 | 0.87 | HDAC6 (0.49) | HDAC6HDAC1 | |
| SCHEMBL26128684 | 0.87 | HDAC6 (0.62) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212707-A | Oxadiazole HDAC6 inhibitors and uses thereof | 艾科尼佐治疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |