SCHEMBL31336115

SCHEMBL31336115

COc1c(-c2noc3cc(CN4CCC(N)CC4)cc(OC)c23)cccc1S(N)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 17/20 0.40
▸ KAT6A Q92794 17/20 0.40
▸ KAT6B Q8WYB5 10/20 0.39
▸ KAT5 Q92993 10/20 0.39
▸ KAT8 Q9H7Z6 10/20 0.39
▸ ACHE P22303 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ SSTR5 P35346 1/20 0.37
▸ HRH1 P35367 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL26123909 0.99 KAT7 (0.40) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31120837 0.81 KAT7 (0.37) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31120840 0.77 CA4 (0.39) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560088 0.77 KAT7 (0.51) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30545810 0.76 KAT7 (0.69) KAT7KAT6AKAT6BKAT5KAT8
Hydrochloric Acid SCHEMBL30545854 0.76 KAT7 (0.68) KAT7KAT6AKAT6BKAT5KAT8
Hydrochloric Acid SCHEMBL26126537 0.76 KAT7 (0.68) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560086 0.71 KAT7 (0.55) KAT7KAT6AKAT6BKAT5KAT8
Hydrochloric Acid SCHEMBL30545765 0.71 KAT7 (0.66) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560082 0.70 KAT7 (0.59) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119301096-A Inhibitors of MYST family lysine acetyltransferase 伊索斯泰里克斯公司 2025-01-10 — — CN disclosed
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