SCHEMBL31336161

SCHEMBL31336161

CC#CN1CCN(c2cccc(-c3cc(OC)c4c(NS(=O)(=O)c5c(OC)cccc5OC)noc4c3)n2)CC1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 20/20 0.51
KAT7 O95251 19/20 0.51
KAT6B Q8WYB5 11/20 0.51
KAT5 Q92993 8/20 0.51
KAT8 Q9H7Z6 8/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31336202 0.89 KAT6A (0.50) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL31336150 0.89 KAT6A (0.49) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26074144 0.87 KAT6A (0.54) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL31336095 0.87 KAT6A (0.53) KAT6AKAT7KAT6BKAT5KAT8
Hydrochloric Acid SCHEMBL30545824 0.86 KAT6A (0.53) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL31336192 0.86 KAT6A (0.53) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30545685 0.85 KAT6A (0.51) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26074142 0.85 KAT6A (0.51) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL31336241 0.84 KAT6A (0.51) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30545790 0.83 KAT6A (0.49) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119301096-A Inhibitors of MYST family lysine acetyltransferase 伊索斯泰里克斯公司 2025-01-10 CN disclosed