Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336845 | 1.00 | SMYD2 (0.35) | SMYD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL31336758 | 1.00 | SMYD2 (0.35) | SMYD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL31336713 | 0.91 | SMYD2 (0.36) | SMYD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL31336836 | 0.91 | SMYD2 (0.36) | SMYD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL31372503 | 0.79 | MGAM (0.37) | SMYD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL31372576 | 0.79 | MGAM (0.37) | SMYD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL31372572 | 0.79 | MGAM (0.37) | SMYD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL31336639 | 0.79 | GBA1 (0.43) | — | |
| SCHEMBL31336704 | 0.78 | SMYD2 (0.37) | SMYD2 | |
| SCHEMBL31336807 | 0.78 | SMYD2 (0.37) | SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |