Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCDIN3D | Q7Z5W3 | 9/20 | 0.47 |
| ▸ | PDE2A | O00408 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23599277 | 0.90 | BCDIN3D (0.48) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL23599045 | 0.89 | PDE2A (0.48) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL23598930 | 0.88 | PDE2A (0.47) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL23598985 | 0.88 | BCDIN3D (0.52) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL30033888 | 0.87 | CA1 (0.60) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL30034952 | 0.85 | PDE2A (0.52) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL23580375 | 0.85 | PDE2A (0.52) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL30034333 | 0.85 | KDM4E (0.48) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL23579868 | 0.85 | CA1 (0.52) | BCDIN3DPDE2ACA1CA2CA9 | |
| SCHEMBL30032869 | 0.85 | CA1 (0.52) | BCDIN3DPDE2ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |