Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PDE2A | O00408 | 4/20 | 0.50 |
| ▸ | BCDIN3D | Q7Z5W3 | 4/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23598948 | 1.00 | MEN1 (0.55) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL23579805 | 0.93 | KMT2A (0.63) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL30032797 | 0.93 | KMT2A (0.63) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL31336930 | 0.89 | PDE2A (0.65) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL31336960 | 0.89 | HIF1A (0.56) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL23579560 | 0.89 | PDE2A (0.65) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL23579889 | 0.89 | HIF1A (0.56) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL31336958 | 0.88 | BCDIN3D (0.59) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL23579917 | 0.88 | BCDIN3D (0.59) | MEN1NPC1KMT2APDE5AHTT | |
| SCHEMBL23580405 | 0.87 | HIF1A (0.51) | MEN1NPC1KMT2APDE5AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |