SCHEMBL3133748

SCHEMBL3133748

CCCCCCC1(C)C(=O)N(Cl)C(=O)N1Cl

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
ALOX12 P18054 1/20 0.33
KMT2A Q03164 1/20 0.33
CPT1A P50416 1/20 0.31
PTGS1 P23219 3/20 0.31
PTGS2 P35354 3/20 0.31
MGLL Q99685 2/20 0.31
FAAH O00519 1/20 0.31
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11023541 0.83 MEN1 (0.32) MEN1GAAALOX12KMT2ACPT1A
SCHEMBL7203617 0.83
SCHEMBL11023740 0.81 POLB (0.30) MEN1GAAALOX12KMT2A
SCHEMBL11872061 0.81 PTGS1 (0.32) MEN1GAAALOX12KMT2APTGS1
SCHEMBL909413 0.76 ELANE (0.31)
SCHEMBL11860846 0.72 PTGS1 (0.35) MEN1GAAALOX12KMT2APTGS1
SCHEMBL11686043 0.70 TYMP (0.33) MEN1GAAALOX12KMT2APTGS1
SCHEMBL4906641 0.68 POLB (0.31)
SCHEMBL5584067 0.66 PTGS1 (0.46) PTGS1PTGS2MGLLFAAHGBA1
SCHEMBL5584310 0.66 PTGS1 (0.46) PTGS1PTGS2MGLLFAAHGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5462617-A Priming substrate with N-halo organic compound, applying heat-curable polyurethane containing polyhydroxy curing agent BANDAG LICENSING CORPORATION (US) 1995-10-31 US claimed
US-5069927-A ACTIVATION OF SURFACE WITH CORONA; FIXING WITH HALOGENATING AG ENT BRIDGESTONE/FIRESTONE, INC. (US) 1991-12-03 US claimed
EP-0386642-A2 Adhesively-bonded coated composites of highly saturated elastomers BRIDGESTONE/FIRESTONE, INC. (US) 1990-09-12 EP claimed
US-4923543-A CURING AN AMINE-CURABLE POLYMER FILLING A CHANNEL BETWEEN A CURED, SOFT, LOW MODULUS ELASTOMER AND THE DAMAGED ELASTOMER ARTICLE BRIDGESTONE/FIRESTONE, INC. (US) 1990-05-08 US claimed
EP-0123070-B1 APPLICATION OF AMBIENT TEMPERATURE CURED POLYMERS OF PREPOLYMERS TO A CURED ELASTOMER THE FIRESTONE TIRE & RUBBER COMPANY (US) 1989-05-03 EP claimed
EP-0122480-B1 AMBIENT TEMPERATURE REPAIR OF ELASTOMERIC ARTICLES HAVING A HOLLOW OR DEFORMITY THEREIN THE FIRESTONE TIRE & RUBBER COMPANY (US) 1989-03-15 EP claimed
US-4798640-A N-HALOHYDANTOIN, N-HALOAMIDE OR N-HALOIMIDE, AMINE CURABLE POLYMER THE FIRESTONE TIRE & RUBBER COMPANY (US) 1989-01-17 US claimed
US-4732196-A TIRE PATCHES THE FIRESTONE TIRE & RUBBER COMPANY (US) 1988-03-22 US claimed
US-4718469-A AMINE CURABLE POLYMER ADHESIVE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1988-01-12 US claimed
EP-0249749-A2 Preformed plug-tire repair THE FIRESTONE TIRE & RUBBER COMPANY (US) 1987-12-23 EP claimed
US-4544427-A Application of ambient temperature cured polymers or prepolymers to a cured elastomer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-10-01 US claimed
EP-0154166-A2 Tire repair by \"patch only\" method THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-09-11 EP claimed
US-4485136-A FILLING HOLLOW, APPYING POLYMER AND AMINE CURING AGENT THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-11-27 US claimed
US-4485135-A APPLYING POLYMER AND AMINE CURING AGENT AND CURING THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-11-27 US claimed
EP-0123070-A2 Application of ambient temperature cured polymers of prepolymers to a cured elastomer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-10-31 EP claimed
EP-0122480-A1 Ambient temperature repair of elastomeric articles having a hollow or deformity therein THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-10-24 EP claimed
US-4434832-A CURING GUM RUBBER IN HOLLOW AREA, APPLYING AMINE CURABLE POLYMER AND CURED PATCH THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-03-06 US claimed
US-4435456-A Application of ambient temperature cured polymers or prepolymers to a cured elastomer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-03-06 US claimed
US-4401145-A Ambient temperature application of indicia to elastomer substrates THE FIRESTONE TIRE & RUBBER COMPANY (US) 1983-08-30 US claimed
US-4311181-A Ambient temperature application of indicia to elastomer substrates THE FIRESTONE TIRE & RUBBER COMPANY (US) 1982-01-19 US claimed