SCHEMBL31338034

SCHEMBL31338034

O=C1CCC(N2Cc3cc(CN4CCC(c5ccnc(Cl)c5Cl)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IKZF2 Q9UKS7 15/20 0.63
IKZF1 Q13422 5/20 0.63
CRBN Q96SW2 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31338336 0.87 IKZF2 (0.65) IKZF2IKZF1
SCHEMBL31338176 0.87 IKZF2 (0.61) IKZF2IKZF1CRBN
SCHEMBL31338247 0.87 IKZF2 (0.55) IKZF2IKZF1CRBN
SCHEMBL31338348 0.87 IKZF1 (0.62) IKZF2IKZF1CRBN
SCHEMBL31338270 0.86 IKZF2 (0.51) IKZF2IKZF1CRBN
SCHEMBL31338048 0.85 IKZF2 (0.65) IKZF2IKZF1CRBN
SCHEMBL31338090 0.85 IKZF2 (0.63) IKZF2IKZF1CRBN
SCHEMBL31279601 0.84 IKZF2 (0.43) IKZF2IKZF1
SCHEMBL31337950 0.84 IKZF2 (0.55) IKZF2IKZF1CRBN
SCHEMBL31338188 0.83 IKZF2 (0.72) IKZF2IKZF1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745137-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-05-20 EP claimed
WO-2025016359-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND 标新生物医药科技(上海)有限公司 2025-01-23 WO claimed
EP-4745137-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-05-20 EP disclosed
WO-2025016359-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND 标新生物医药科技(上海)有限公司 2025-01-23 WO disclosed