SCHEMBL31338065

SCHEMBL31338065

O=C1CCC(N2Cc3cc(CN4CC=C(c5ccnc(F)c5F)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IKZF1 Q13422 5/20 0.64
IKZF2 Q9UKS7 11/20 0.53
CRBN Q96SW2 3/20 0.47
WIZ O95785 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31338347 0.88 IKZF1 (0.66) IKZF1IKZF2CRBNWIZ
SCHEMBL31338263 0.86 IKZF1 (0.49) IKZF1IKZF2CRBN
SCHEMBL31338356 0.85 IKZF1 (0.65) IKZF1IKZF2CRBNWIZ
SCHEMBL31337991 0.84 IKZF1 (0.68) IKZF1IKZF2CRBNWIZ
SCHEMBL31338223 0.84 IKZF1 (0.65) IKZF1IKZF2CRBNWIZ
SCHEMBL31338289 0.83 IKZF2 (0.57) IKZF1IKZF2CRBN
SCHEMBL31338336 0.83 IKZF2 (0.65) IKZF1IKZF2
SCHEMBL31338394 0.83 IKZF1 (0.68) IKZF1IKZF2CRBN
SCHEMBL31279571 0.82 IKZF1 (0.41) IKZF1IKZF2
SCHEMBL31338354 0.82 IKZF1 (0.71) IKZF1IKZF2CRBNWIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025016359-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND 标新生物医药科技(上海)有限公司 2025-01-23 WO claimed
WO-2025016359-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND 标新生物医药科技(上海)有限公司 2025-01-23 WO disclosed