Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.59 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.59 |
| ▸ | IKZF1 | Q13422 | 4/20 | 0.57 |
| ▸ | WIZ | O95785 | 1/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31337945 | 0.93 | CRBN (0.66) | IKZF2CRBNIKZF3IKZF1WIZ | |
| SCHEMBL31338010 | 0.92 | CRBN (0.70) | IKZF2CRBNIKZF3IKZF1DDB1 | |
| SCHEMBL31337958 | 0.90 | IKZF2 (0.59) | IKZF2CRBNIKZF3IKZF1WIZ | |
| SCHEMBL31337936 | 0.89 | IKZF2 (0.56) | IKZF2CRBNIKZF3IKZF1WIZ | |
| SCHEMBL25236187 | 0.89 | CRBN (0.65) | IKZF2CRBNIKZF3IKZF1WIZ | |
| SCHEMBL31076835 | 0.89 | CRBN (0.65) | IKZF2CRBNIKZF3IKZF1WIZ | |
| SCHEMBL31338287 | 0.88 | IKZF2 (0.60) | IKZF2CRBNIKZF3IKZF1WIZ | |
| SCHEMBL31338224 | 0.87 | IKZF2 (0.59) | IKZF2CRBNIKZF3IKZF1WIZ | |
| SCHEMBL25230219 | 0.87 | IKZF2 (0.58) | IKZF2CRBNIKZF3IKZF1WIZ | |
| SCHEMBL31338308 | 0.87 | IKZF2 (0.61) | IKZF2CRBNIKZF3IKZF1WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4745137-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | claimed |
| WO-2025016359-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | 标新生物医药科技(上海)有限公司 | 2025-01-23 | — | — | WO | claimed |
| EP-4745137-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025016359-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | 标新生物医药科技(上海)有限公司 | 2025-01-23 | — | — | WO | disclosed |