Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF1 | Q13422 | 2/20 | 0.51 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.47 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31338058 | 0.86 | IKZF1 (0.65) | IKZF1IKZF2CRBNGSPT1DDB1 | |
| SCHEMBL31338340 | 0.86 | IKZF1 (0.54) | IKZF1IKZF2CRBNGSPT1DDB1 | |
| SCHEMBL31337972 | 0.86 | IKZF1 (0.50) | IKZF1IKZF2CRBNGSPT1DDB1 | |
| SCHEMBL31338312 | 0.85 | IKZF1 (0.55) | IKZF1IKZF2CRBNGSPT1DDB1 | |
| SCHEMBL31338295 | 0.85 | IKZF1 (0.51) | IKZF1IKZF2CRBNGSPT1DDB1 | |
| SCHEMBL31338360 | 0.82 | IKZF1 (0.53) | IKZF1IKZF2CRBNGSPT1DDB1 | |
| SCHEMBL31278810 | 0.82 | IKZF1 (0.38) | IKZF1IKZF2 | |
| SCHEMBL31338124 | 0.82 | CRBN (0.51) | CRBNGSPT1DDB1ALDH1A1CHRM2 | |
| SCHEMBL31338274 | 0.82 | IKZF2 (0.52) | IKZF2CRBNGSPT1DDB1ALDH1A1 | |
| SCHEMBL31337973 | 0.81 | IKZF1 (0.53) | IKZF1IKZF2CRBNDDB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4745137-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | claimed |
| WO-2025016359-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | 标新生物医药科技(上海)有限公司 | 2025-01-23 | — | — | WO | claimed |
| EP-4745137-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025016359-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | 标新生物医药科技(上海)有限公司 | 2025-01-23 | — | — | WO | disclosed |