SCHEMBL31338334

SCHEMBL31338334

O=C1CCC(N2Cc3cc(CN4CCN(c5cccc(Cl)n5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IKZF1 Q13422 5/20 0.56
CRBN Q96SW2 8/20 0.56
IKZF3 Q9UKT9 6/20 0.56
IKZF2 Q9UKS7 8/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31338352 0.91 IKZF1 (0.57) IKZF1CRBNIKZF3IKZF2
SCHEMBL31338403 0.90 IKZF2 (0.58) IKZF1CRBNIKZF3IKZF2
SCHEMBL25647384 0.88 IKZF2 (0.55) IKZF1CRBNIKZF3IKZF2
SCHEMBL31076539 0.88 IKZF2 (0.55) IKZF1CRBNIKZF3IKZF2
SCHEMBL31338158 0.88 IKZF1 (0.56) IKZF1CRBNIKZF3IKZF2
SCHEMBL31338120 0.87 IKZF1 (0.58) IKZF1CRBNIKZF3IKZF2
SCHEMBL31338145 0.86 CRBN (0.68) IKZF1CRBNIKZF3IKZF2
SCHEMBL31338332 0.86 IKZF2 (0.56) IKZF1CRBNIKZF3IKZF2
SCHEMBL31338045 0.86 IKZF2 (0.57) IKZF1CRBNIKZF3IKZF2
SCHEMBL25226548 0.85 IKZF2 (0.65) IKZF1CRBNIKZF3IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745137-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-05-20 EP claimed
WO-2025016359-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND 标新生物医药科技(上海)有限公司 2025-01-23 WO claimed
EP-4745137-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-05-20 EP disclosed
WO-2025016359-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND 标新生物医药科技(上海)有限公司 2025-01-23 WO disclosed