Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | AR | P10275 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | GUSB | P08236 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196491 | 1.00 | TUBB1 (0.64) | TUBB1MAOBARNR1H4MCL1 | |
| SCHEMBL7196488 | 1.00 | TUBB1 (0.64) | TUBB1MAOBARNR1H4MCL1 | |
| SCHEMBL31436373 | 0.86 | CHRNA7 (0.60) | TUBB1MAOBARNR1H4MCL1 | |
| SCHEMBL31436353 | 0.86 | CHRNA7 (0.60) | TUBB1MAOBARNR1H4MCL1 | |
| SCHEMBL7196513 | 0.85 | TUBB1 (0.67) | TUBB1MAOBARMCL1CHRNA7 | |
| SCHEMBL31436365 | 0.85 | TUBB1 (0.67) | TUBB1MAOBARMCL1CHRNA7 | |
| SCHEMBL7196511 | 0.85 | TUBB1 (0.67) | TUBB1MAOBARMCL1CHRNA7 | |
| SCHEMBL30282145 | 0.84 | CHRNA7 (0.72) | TUBB1NR1H4MCL1MAPTNPC1 | |
| SCHEMBL20340323 | 0.84 | MAOB (0.71) | MAOBARNR1H4MAPTNPC1 | |
| SCHEMBL31230210 | 0.83 | TUBB1 (0.64) | TUBB1MCL1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115624544-B | Application of chalcone analogue as active substance in preparation of antitumor drugs | 甘肃中医药大学 | 2025-01-24 | — | — | CN | disclosed |