Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | TP53 | P04637 | 7/20 | 0.66 |
| ▸ | APP | P05067 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11011832 | 0.89 | MAPT (0.69) | MAPTTP53APPSMN1; SMN2LMNA | |
| SCHEMBL11037107 | 0.86 | MAPT (0.68) | MAPTTP53APPSMN1; SMN2LMNA | |
| SCHEMBL13198354 | 0.82 | TP53 (0.70) | MAPTTP53APPSMN1; SMN2LMNA | |
| SCHEMBL31338708 | 0.81 | MAPT (0.67) | MAPTTP53APPSMN1; SMN2LMNA | |
| SCHEMBL31338700 | 0.81 | MAPT (0.80) | MAPTTP53SMN1; SMN2LMNARAB9A | |
| SCHEMBL31338702 | 0.81 | MAPT (0.80) | MAPTTP53SMN1; SMN2LMNARAB9A | |
| SCHEMBL11011840 | 0.80 | MAPT (0.60) | MAPTTP53APPSMN1; SMN2LMNA | |
| SCHEMBL796966 | 0.78 | APP (0.83) | MAPTTP53APPSMN1; SMN2LMNA | |
| SCHEMBL29924606 | 0.78 | MAPT (0.51) | MAPTTP53APPSMN1; SMN2LMNA | |
| SCHEMBL11004214 | 0.78 | FLT3 (0.53) | MAPTTP53APPSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4741401-A1 | BENZOTHIAZOIMIDAZOLYL COMPOUND AND USE THEREOF | ER Stress Research Institute, Inc. (JP) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025009553-A1 | BENZOTHIAZOIMIDAZOLYL COMPOUND AND USE THEREOF | 小胞体ストレス研究所株式会社 | 2025-01-09 | — | — | WO | disclosed |