Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349937 | 0.76 | IGF1R (0.52) | CDK2GSK3BIGF1R | |
| SCHEMBL3026520 | 0.75 | CDK2 (0.60) | RAB9ACDK2MAPK1GSK3BCHEK1 | |
| SCHEMBL5534364 | 0.70 | GAA (0.62) | RAB9APOLBL3MBTL1MAPK1ADORA3 | |
| SCHEMBL1019383 | 0.70 | IP6K1 (0.47) | RAB9APOLBCDK2MAPK1ADORA3 | |
| SCHEMBL4409376 | 0.69 | KDR (0.48) | CDK2ADORA3TYRO3IGF1R | |
| SCHEMBL4551624 | 0.69 | FLT3 (0.44) | RAB9ACDK2TYRO3NPC1SMN1; SMN2 | |
| SCHEMBL680853 | 0.69 | NPC1 (0.45) | RAB9AMAPK1ADORA3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL7659966 | 0.68 | CDK1 (0.58) | CDK2CHEK1GAAMAPTIGF1R | |
| Hydrochloric Acid SCHEMBL4456673 | 0.68 | NPC1 (0.44) | RAB9AMAPK1ADORA3ADORA2AADORA1 | |
| SCHEMBL4480587 | 0.66 | KDM4E (0.33) | CDK2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |