Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2F2 | P24468 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 4/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | JAK1 | P23458 | 4/20 | 0.42 |
| ▸ | JAK3 | P52333 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FOS | P01100 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050288 | 0.91 | NR2F2 (0.56) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL4070421 | 0.89 | NR2F2 (0.62) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL761164 | 0.89 | NR2F2 (0.60) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL29501978 | 0.87 | NR2F2 (0.63) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL20299361 | 0.87 | NR2F2 (0.63) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL23452672 | 0.86 | NR2F2 (0.53) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL20329838 | 0.86 | NR2F2 (0.53) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL30736374 | 0.86 | NR2F2 (0.53) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL20299341 | 0.86 | NR2F2 (0.53) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL23620674 | 0.85 | NR2F2 (0.52) | NR2F2NPSR1KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049247-A1 | 5,6-CORE SILACYCLE BASED INHIBITORS OF DNA-DEPENDENT PROTEIN KINASE AND COMPOSITIONS AND APPLICATION IN GENE EDITING | JUNO THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |