Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 20/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342892 | 0.84 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342843 | 0.82 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342960 | 0.82 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342934 | 0.81 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342867 | 0.81 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342855 | 0.81 | CYP3A4 (0.50) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31343076 | 0.80 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342901 | 0.79 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342924 | 0.75 | CYP3A4 (0.41) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342948 | 0.74 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |