Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 20/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343098 | 0.86 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342919 | 0.85 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31343046 | 0.85 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342855 | 0.83 | CYP3A4 (0.50) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31343006 | 0.83 | CYP3A4 (0.50) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342810 | 0.80 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342992 | 0.80 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31343040 | 0.78 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342972 | 0.77 | HTR2C (0.43) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342973 | 0.77 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |