SCHEMBL31344600

SCHEMBL31344600

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NC[C@H]5CCCOC5)c([N+](=O)[O-])c4)c(Oc4ccc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 7/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1813026 1.00 BCL2 (1.00) BCL2
SCHEMBL1702665 1.00 BCL2 (1.00) BCL2
SCHEMBL1956299 1.00 BCL2 (1.00) BCL2
SCHEMBL30468002 0.95 BCL2 (1.00) BCL2
SCHEMBL1702539 0.95 BCL2 (1.00) BCL2
SCHEMBL1957657 0.95 BCL2 (0.92) BCL2
SCHEMBL19424738 0.94 BCL2 (0.88) BCL2
SCHEMBL19424858 0.94 BCL2 (0.88) BCL2
SCHEMBL19424909 0.94 BCL2 (0.88) BCL2
SCHEMBL19419621 0.93 BCL2 (0.92) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
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