SCHEMBL31344638

SCHEMBL31344638

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4cnc(NCC5CN(C6CC6)CCO5)c(Cl)c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701589 1.00 BCL2 (1.00) BCL2
SCHEMBL31344637 1.00 BCL2 (1.00) BCL2
SCHEMBL1701042 0.94 BCL2 (1.00) BCL2
SCHEMBL31344624 0.94 BCL2 (1.00) BCL2
SCHEMBL1700540 0.92 BCL2 (1.00) BCL2
SCHEMBL31344628 0.92 BCL2 (1.00) BCL2
SCHEMBL32663553 0.91 BCL2 (1.00) BCL2
SCHEMBL1701137 0.91 BCL2 (1.00) BCL2
SCHEMBL1702062 0.91 BCL2 (1.00) BCL2
SCHEMBL31344605 0.91 BCL2 (1.00) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
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