SCHEMBL31344640

SCHEMBL31344640

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(OC[C@H]5CC[C@H](O)CC5)c(Cl)c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700535 1.00 BCL2 (1.00) BCL2
SCHEMBL1700532 1.00 BCL2 (1.00) BCL2
SCHEMBL1700827 0.95 BCL2 (1.00) BCL2
SCHEMBL30314097 0.95 BCL2 (1.00) BCL2
SCHEMBL1700825 0.95 BCL2 (1.00) BCL2
SCHEMBL1700829 0.95 BCL2 (1.00) BCL2
SCHEMBL19424491 0.95 BCL2 (0.91) BCL2
SCHEMBL1702404 0.95 BCL2 (0.91) BCL2
SCHEMBL1869526 0.94 BCL2 (0.90) BCL2
SCHEMBL1700720 0.94 BCL2 (0.92) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 — — EP disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
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