SCHEMBL31344645

SCHEMBL31344645

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(N[C@H]5CC[C@@H](NC6CC6)CC5)c([N+](=O)[O-])c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 0.92

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 20/20 0.92

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1699888 1.00 BCL2 (0.92) BCL2
SCHEMBL1699890 1.00 BCL2 (0.92) BCL2
SCHEMBL29657429 1.00 BCL2 (0.92) BCL2
SCHEMBL1699968 0.98 BCL2 (0.91) BCL2
SCHEMBL1699975 0.98 BCL2 (0.91) BCL2
SCHEMBL31344634 0.98 BCL2 (0.91) BCL2
SCHEMBL30314070 0.96 BCL2 (1.00) BCL2
SCHEMBL1701625 0.96 BCL2 (1.00) BCL2
SCHEMBL1699828 0.96 BCL2 (0.89) BCL2
SCHEMBL1700063 0.96 BCL2 (0.89) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
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