SCHEMBL31344652

CC1(C)CC(c2ccc(Cl)cc2)=C(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc([Au][C@H]5CC[C@H](N6CCOCC6)CC5)c(S(=O)(=O)C(F)(F)F)c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)CO1

nearest known ligand 0.78

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	BCL2	P10415	20/20	0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30468044	0.92	BCL2 (0.82)	BCL2
SCHEMBL1701576	0.92	BCL2 (0.82)	BCL2
SCHEMBL1700689	0.92	BCL2 (0.82)	BCL2
SCHEMBL20916255	0.88	BCL2 (0.72)	BCL2
SCHEMBL1699782	0.88	BCL2 (1.00)	BCL2
SCHEMBL30314051	0.86	BCL2 (0.81)	BCL2
SCHEMBL1700810	0.86	BCL2 (0.81)	BCL2
SCHEMBL1700654	0.85	BCL2 (0.87)	BCL2
SCHEMBL1701552	0.85	BCL2 (0.87)	BCL2
SCHEMBL31344659	0.85	BCL2 (0.87)	BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4474383-A2	APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES	AbbVie Ireland Unlimited Company (IE)	2024-12-11	—	—	EP	disclosed