Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31344686 | 0.84 | PLAU (0.34) | PLAU | |
| SCHEMBL31344675 | 0.84 | PLAU (0.37) | PLAUPLAT | |
| SCHEMBL31344743 | 0.81 | NPSR1 (0.41) | PLAUGAARAB9ANPSR1LMNA | |
| SCHEMBL31344701 | 0.76 | PLAU (0.31) | PLAUPLATNPSR1 | |
| SCHEMBL31344698 | 0.74 | IDO1 (0.43) | PLAUPLGPLATGAASMN1; SMN2 | |
| SCHEMBL31344756 | 0.74 | PLAU (0.34) | PLAUNPSR1 | |
| SCHEMBL31344744 | 0.74 | NPSR1 (0.41) | PLAUNPSR1 | |
| SCHEMBL31344777 | 0.68 | PLAU (0.36) | PLAUPLATKDM4E | |
| SCHEMBL31344736 | 0.67 | NPSR1 (0.48) | PLAUGAASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL4586975 | 0.66 | PLAU (0.40) | PLAUGAASMN1; SMN2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724447-A1 | SYNTHESIS OF CYCLIC ACYL SULFOXIMINES | Syngenta Crop Protection AG (CH) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024252006-A1 | SYNTHESIS OF CYCLIC ACYL SULFOXIMINES | SYNGENTA CROP PROTECTION AG (CH) | 2024-12-12 | — | — | WO | disclosed |