SCHEMBL31344710

SCHEMBL31344710

COCCNc1ccc(S(=O)(=O)NC(=O)c2ccc(N3CCN(CC4=C(c5ccc(Cl)cc5)CC(C)(C)CC4)CC3)cc2Oc2ccc3[nH]ccc3c2)cc1S(=O)(=O)C(F)(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702489 1.00 BCL2 (1.00) BCL2
SCHEMBL1955082 0.93 BCL2 (0.88) BCL2
SCHEMBL1955765 0.93 BCL2 (0.87) BCL2
SCHEMBL1955253 0.93 BCL2 (0.87) BCL2
SCHEMBL1958464 0.92 BCL2 (0.86) BCL2
SCHEMBL1699798 0.92 BCL2 (1.00) BCL2
SCHEMBL30313867 0.92 BCL2 (1.00) BCL2
SCHEMBL1702039 0.91 BCL2 (1.00) BCL2
SCHEMBL31344674 0.91 BCL2 (1.00) BCL2
SCHEMBL1958253 0.91 BCL2 (0.83) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
Send feedback