SCHEMBL31344724

SCHEMBL31344724

O=C(NS(=O)(=O)c1ccc(NCCCN2CCOCC2)c([N+](=O)[O-])c1)c1ccc(N2CCN(Cc3ccccc3-c3ccc(Cl)cc3)CC2)cc1Oc1ccc2[nH]ccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 14/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1810020 1.00 BCL2 (1.00) BCL2
SCHEMBL1957119 0.93 BCL2 (0.93) BCL2
SCHEMBL1956079 0.93 BCL2 (1.00) BCL2
SCHEMBL19424824 0.92 BCL2 (0.86) BCL2
SCHEMBL1810909 0.92 BCL2 (0.85) BCL2
SCHEMBL30313874 0.92 BCL2 (0.85) BCL2
SCHEMBL1957513 0.92 BCL2 (0.85) BCL2
SCHEMBL1956315 0.91 BCL2 (1.00) BCL2
SCHEMBL1957374 0.91 BCL2 (0.97) BCL2
SCHEMBL1810749 0.91 BCL2 (1.00) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
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