SCHEMBL31345398

SCHEMBL31345398

OCc1cc(OC2CC2)ccc1F

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 4/20 0.51
▸ MLNR O43193 1/20 0.44
▸ PTGS1 P23219 1/20 0.40
▸ PTGS2 P35354 1/20 0.40
▸ GPR119 Q8TDV5 1/20 0.37
▸ MTNR1B P49286 1/20 0.36
▸ EPHX2 P34913 2/20 0.36
▸ GRIN1 Q05586 1/20 0.36
▸ GRIN2B Q13224 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ FFAR1 O14842 1/20 0.35
▸ APP P05067 2/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ ACACB O00763 1/20 0.35
▸ CACNA1H O95180 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12093157 0.86 FFAR4 (0.41) FFAR4MLNRPTGS1PTGS2MTNR1B
SCHEMBL31345444 0.83 FFAR4 (0.42) FFAR4MLNRPTGS1PTGS2MTNR1B
SCHEMBL20972028 0.79 FFAR4 (0.36) FFAR4MLNRPTGS1PTGS2EPHX2
SCHEMBL23434787 0.79 PTGS1 (0.44) FFAR4MLNRPTGS1PTGS2MTNR1B
SCHEMBL24716435 0.77 PTGS1 (0.46) FFAR4PTGS1PTGS2GPR119EPHX2
SCHEMBL6565551 0.77 PTGS1 (0.48) FFAR4PTGS1PTGS2EPHX2ALDH1A1
SCHEMBL16950678 0.77 NQO1 (0.48) FFAR4ALDH1A1TSHRFFAR1
SCHEMBL697670 0.74 CHRM2 (0.50) MTNR1BALDH1A1
SCHEMBL16483442 0.73 HTR2C (0.46) FFAR4PTGS1PTGS2GPR119EPHX2
SCHEMBL15057385 0.73 FFAR4 (0.42) FFAR4PTGS1PTGS2GPR119EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739669-A1 SODIUM CHANNEL BLOCKERS Novartis AG (CH) 2026-05-13 — — EP disclosed
US-20250034108-A1 SODIUM CHANNEL BLOCKERS NOVARTIS AG (CH) 2025-01-30 — — US disclosed
WO-2025011450-A1 SODIUM CHANNEL BLOCKERS NOVARTIS AG (CH) 2025-01-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034108-A1 SODIUM CHANNEL BLOCKERS SCN5A, SCN2B, SCN1B FFAR4 2044/4885MLNR 1182/4885PTGS1 1925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback