Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26617989 | 1.00 | KDM4E (0.54) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL15491396 | 0.88 | MEN1 (0.57) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL26617549 | 0.85 | POLB (0.53) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL5381896 | 0.85 | KDM4E (0.56) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL30681986 | 0.85 | KDM4E (0.56) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL8577094 | 0.79 | SMN1; SMN2 (0.61) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL2879866 | 0.77 | POLB (0.68) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL2443270 | 0.77 | MEN1 (0.71) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL38662586 | 0.77 | MEN1 (0.71) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL23860957 | 0.76 | NR4A2 (0.51) | KDM4EMEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585247-A | Bicyclic heterocyclic amide inhibitors of nav1.8 for the treatment of pain | 赛特温治疗公司 | 2025-03-07 | — | — | CN | disclosed |