SCHEMBL31345665

SCHEMBL31345665

Cc1cccc(OCC(C)C)c1-n1nc2c(c1-c1ccc(N)c(F)c1)CN(C(=O)OC(C)(C)C)CC2

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21074105 1.00 C5AR1 (0.75) C5AR1
SCHEMBL31345683 0.91 C5AR1 (0.68) C5AR1
SCHEMBL21074112 0.91 C5AR1 (0.68) C5AR1
SCHEMBL21074106 0.90 C5AR1 (0.81) C5AR1
SCHEMBL31345702 0.90 C5AR1 (0.81) C5AR1
SCHEMBL21074097 0.90 C5AR1 (0.70) C5AR1
SCHEMBL31345679 0.90 C5AR1 (0.70) C5AR1
SCHEMBL31345715 0.90 C5AR1 (0.70) C5AR1
SCHEMBL21139487 0.89 C5AR1 (0.72) C5AR1
SCHEMBL21074078 0.89 C5AR1 (0.73) C5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111788185-B Diaryl substituted 6,5 fused ring compounds as C5a inhibitors 凯莫森特里克斯股份有限公司 2024-12-13 CN disclosed