SCHEMBL31345700

SCHEMBL31345700

NNC(=O)c1cncc(N)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.65
ALDH1A1 P00352 6/20 0.62
LMNA P02545 3/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
DDO Q99489 1/20 0.62
MPO P05164 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP1A2 P05177 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2A6 P11509 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAPT P10636 4/20 0.44
POLB P06746 2/20 0.44
GAA P10253 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
BLM P54132 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NSD2 O96028 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6755703 1.00 KDM4E (0.65) KDM4EALDH1A1LMNAMEN1KMT2A
SCHEMBL28983957 0.87 KDM4E (0.74) KDM4EALDH1A1LMNAMEN1KMT2A
SCHEMBL14865465 0.82 KDM4E (0.60) KDM4EALDH1A1LMNAMEN1KMT2A
SCHEMBL3934325 0.82 KDM4E (0.60) KDM4EALDH1A1LMNAMEN1KMT2A
SCHEMBL31226416 0.82 KDM4E (0.55) KDM4EALDH1A1LMNAMEN1KMT2A
SCHEMBL13279530 0.80 KDM4E (0.53) KDM4EALDH1A1LMNAMEN1KMT2A
SCHEMBL27750302 0.79 KDM4E (0.72) KDM4EALDH1A1LMNAMEN1KMT2A
SCHEMBL1334377 0.78 KDM4E (0.62) KDM4EALDH1A1LMNAMPOCYP3A4
SCHEMBL31418070 0.78 KDM4E (1.00) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL5479141 0.78 KDM4E (0.62) KDM4EALDH1A1LMNAMPOCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569701-A Preparation and application of compound with 1H-benzimidazole structure 江西中医药大学 2025-03-07 CN disclosed