Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134642 | 1.00 | AR (0.39) | ARALDH1A1MAPT | |
| SCHEMBL13271067 | 1.00 | AR (0.39) | ARALDH1A1MAPT | |
| SCHEMBL13271004 | 0.82 | AR (0.35) | AR | |
| SCHEMBL3125455 | 0.82 | AR (0.35) | AR | |
| Water SCHEMBL3257184 | 0.82 | AR (0.35) | AR | |
| SCHEMBL3125461 | 0.82 | AR (0.35) | AR | |
| Water SCHEMBL3255068 | 0.82 | AR (0.35) | AR | |
| SCHEMBL13480441 | 0.82 | AR (0.35) | AR | |
| SCHEMBL3129920 | 0.82 | AR (0.35) | AR | |
| SCHEMBL3136723 | 0.82 | AR (0.35) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991223-B1 | NOVEL IMIDAZOLOPYRAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-07-14 | — | — | EP | disclosed |
| US-7655683-B2 | Imidazolopyrazole derivatives useful as selective androgen receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2010-02-02 | — | — | US | disclosed |
| US-20070197616-A1 | NOVEL IMIDAZOLOPYRAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197616-A1 | NOVEL IMIDAZOLOPYRAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | AR, NR5A1, NR5A2 | AR 1/4885ALDH1A1 1389/4885MAPT 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.