Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566459 | 1.00 | GAA (0.43) | GAAALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL3465072 | 0.87 | TSHR (0.44) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3465075 | 0.87 | TSHR (0.44) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL2638245 | 0.86 | GAA (0.40) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3139233 | 0.86 | GAA (0.40) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4553899 | 0.86 | GAA (0.40) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3148191 | 0.85 | GAA (0.39) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3258665 | 0.84 | GAA (0.39) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL169067 | 0.83 | GAA (0.40) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL231822 | 0.83 | GAA (0.40) | GAAALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-B1 | FUNGICIDAL AMIDES | DU PONT (US) | 2014-12-31 | — | — | EP | claimed |
| US-8420673-B2 | Fungicidal amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-16 | — | — | US | claimed |
| US-20100004288-A1 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-07 | — | — | US | claimed |
| EP-2121660-B1 | FUNGICIDAL AMIDES | DU PONT (US) | 2014-12-31 | — | — | EP | disclosed |
| US-8420673-B2 | Fungicidal amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100004288-A1 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004288-A1 | FUNGICIDAL AMIDES | NAT1, NOX1, Q6ZSR9 | GAA 90/4885ALDH1A1 662/4885MEN1 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.