Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21995291 | 1.00 | PDE10A (0.40) | PDE10AKMT2ATHRBTET2TET1 | |
| SCHEMBL22056700 | 0.83 | KMT2A (0.41) | PDE10AKMT2ATHRBTET2TET1 | |
| SCHEMBL21995357 | 0.83 | KMT2A (0.41) | PDE10AKMT2ATHRBMEN1GAA | |
| SCHEMBL22056701 | 0.79 | KMT2A (0.46) | KMT2AMEN1GAAATMALDH1A1 | |
| SCHEMBL22056836 | 0.77 | CDK4 (0.40) | MAT2A | |
| SCHEMBL12496048 | 0.77 | KDM4E (0.46) | PDE10AKMT2ATET2TET1MEN1 | |
| SCHEMBL24182573 | 0.76 | RXFP1 (0.39) | PDE10AKMT2ATHRBMEN1GAA | |
| SCHEMBL21351383 | 0.75 | ATM (0.41) | PDE10AKMT2AMEN1GAAMAPT | |
| SCHEMBL21636122 | 0.74 | KMT2A (0.52) | PDE10AKMT2AMEN1GAAATM | |
| SCHEMBL14933478 | 0.74 | KMT2A (0.47) | PDE10AKMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12250880-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2025-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12250880-B2 | Compounds for electronic devices | ETV6, CYP2C19, ESR1 | PDE10A 2563/4885KMT2A 1896/4885THRB 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.