Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 4/20 | 0.55 |
| ▸ | PLK1 | P53350 | 9/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | INSR | P06213 | 2/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133770 | 0.94 | PLK1 (0.59) | IGF1RPLK1INSRALK | |
| SCHEMBL3133005 | 0.90 | IGF1R (0.68) | IGF1RPLK1TTKINSRALK | |
| SCHEMBL3120115 | 0.89 | IGF1R (0.52) | IGF1RPLK1EGFRINSRALK | |
| SCHEMBL2207868 | 0.87 | IGF1R (0.51) | IGF1RPLK1FGFR1CAMK2DTTK | |
| SCHEMBL2208501 | 0.87 | IGF1R (0.53) | IGF1RPLK1FGFR1CAMK2DTTK | |
| SCHEMBL2205196 | 0.86 | IGF1R (0.60) | IGF1RPLK1FGFR1CAMK2DTTK | |
| SCHEMBL3129871 | 0.84 | IGF1R (0.51) | IGF1RPLK1INSRALK | |
| SCHEMBL3125058 | 0.83 | PLK1 (0.49) | IGF1RPLK1EGFRINSRALK | |
| SCHEMBL2207593 | 0.82 | IGF1R (0.51) | IGF1RPLK1EGFRINSRALK | |
| SCHEMBL2207865 | 0.81 | MAPK10 (0.65) | IGF1RPLK1FGFR1CAMK2DEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045451-A1 | PYRROLOPYRIMIDINE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-22 | — | — | WO | disclosed |