SCHEMBL31348944

SCHEMBL31348944

O=C(Nc1c(Br)cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc1C(F)F)c1cccc(N(O)C(=O)c2ccc(F)cc2)c1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31348918 0.88 KDM4E (0.31) KDM4E
SCHEMBL31348965 0.88 HDAC8 (0.32) KDM4E
SCHEMBL31348979 0.86 BRAF (0.34)
SCHEMBL31348867 0.86 KDM4E (0.31) KDM4E
SCHEMBL29161231 0.85
SCHEMBL31348975 0.84 SMN1; SMN2 (0.33) KDM4E
SCHEMBL31348940 0.84 HTT (0.36) KDM4E
SCHEMBL1766370 0.83 KDM4E (0.35) KDM4E
SCHEMBL29161211 0.82 RXFP1 (0.35)
SCHEMBL31348953 0.80 HTT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119059936-A Meta-aminobenzoic acid bisamide compound 湖南化工研究院有限公司 2024-12-03 CN claimed
CN-119059936-A Meta-aminobenzoic acid bisamide compound 湖南化工研究院有限公司 2024-12-03 CN disclosed