Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134889 | 1.00 | AVPR1B (0.76) | AVPR1B | |
| SCHEMBL3554670 | 0.86 | AVPR1B (0.56) | AVPR1B | |
| SCHEMBL3130341 | 0.83 | AVPR1B (0.69) | AVPR1B | |
| SCHEMBL3130335 | 0.83 | AVPR1B (0.69) | AVPR1B | |
| SCHEMBL3125540 | 0.81 | AVPR1B (1.00) | AVPR1B | |
| SCHEMBL3134197 | 0.81 | AVPR1B (0.88) | AVPR1B | |
| SCHEMBL3132088 | 0.80 | AVPR1B (1.00) | AVPR1B | |
| SCHEMBL3554672 | 0.80 | AVPR1B (0.51) | AVPR1B | |
| SCHEMBL3554674 | 0.80 | AVPR1B (0.51) | AVPR1B | |
| SCHEMBL3132973 | 0.80 | AVPR1B (1.00) | AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861380-B1 | 2-(4-OXO-4H-QUINAZOLIN-3-YL)ACETAMIDES AND THEIR USE AS VASOPRESSIN V3 ANTAGONISTS | ORGANON NV (NL) | 2010-07-07 | — | — | EP | disclosed |