Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.31 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31577979 | 0.81 | MAP4K4 (0.32) | MAP4K4RPS6KA5RPS6KA4ELANECDK2 | |
| SCHEMBL31463869 | 0.80 | KDM5A (0.34) | — | |
| SCHEMBL31463697 | 0.76 | KDM4E (0.32) | — | |
| SCHEMBL12875621 | 0.74 | CDK2 (0.41) | CDK2 | |
| SCHEMBL24393128 | 0.69 | EGLN2 (0.33) | CDK2 | |
| SCHEMBL20263135 | 0.68 | CFTR (0.36) | — | |
| SCHEMBL24392520 | 0.67 | EGLN2 (0.33) | — | |
| SCHEMBL24392514 | 0.67 | KDR (0.35) | — | |
| SCHEMBL24392182 | 0.65 | PIK3CG (0.33) | — | |
| SCHEMBL4112547 | 0.64 | MAP4K4 (0.34) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013030-A | Inhibitors of CDK4/6 kinase | 金耐特生物制药公司 | 2024-11-22 | — | — | CN | disclosed |