Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31351066 | 0.92 | IRAK4 (0.54) | IRAK4IRAK1KCNH2CHEK1MAPK1 | |
| SCHEMBL31351018 | 0.88 | IRAK4 (0.49) | IRAK4IRAK1KCNH2HPGDCHEK1 | |
| SCHEMBL31350809 | 0.87 | IRAK4 (0.48) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL31351056 | 0.85 | IRAK4 (0.45) | IRAK4IRAK1KCNH2HPGDCHEK1 | |
| SCHEMBL31350999 | 0.85 | IRAK4 (0.45) | IRAK4CHEK1LMNAMAPT | |
| SCHEMBL31351246 | 0.85 | IRAK4 (0.46) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL31350911 | 0.82 | IRAK4 (0.41) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL31351174 | 0.82 | IRAK4 (0.51) | IRAK4IRAK1HPGDCHEK1 | |
| SCHEMBL31351132 | 0.82 | IRAK4 (0.54) | IRAK4IRAK1CHEK1MAPK1 | |
| SCHEMBL31351231 | 0.81 | IRAK4 (0.50) | IRAK4IRAK1CHEK1LMNACSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003987-A1 | NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 동화약품주식회사 | 2025-01-02 | — | — | WO | disclosed |