Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133750 | 0.92 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4MAP4K4 | |
| SCHEMBL3137400 | 0.91 | S1PR1 (0.53) | S1PR1S1PR3S1PR5S1PR4MAP4K4 | |
| SCHEMBL3125033 | 0.91 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4MAP4K4 | |
| SCHEMBL3128391 | 0.90 | S1PR1 (0.67) | S1PR1S1PR3S1PR5S1PR4MAP4K4 | |
| SCHEMBL3132696 | 0.90 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL3128858 | 0.88 | S1PR1 (0.45) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL3137868 | 0.87 | S1PR1 (0.56) | S1PR1S1PR3S1PR5S1PR4MAP4K4 | |
| SCHEMBL3135528 | 0.84 | S1PR1 (0.57) | S1PR1S1PR3S1PR5S1PR4MAP4K4 | |
| SCHEMBL3133591 | 0.82 | S1PR1 (0.58) | S1PR1S1PR3S1PR5S1PR4MAP4K4 | |
| SCHEMBL3141824 | 0.81 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873153-B1 | 3-AZETIDINECARBOXYLIC ACID DERIVATIVES FOR USE AS IMMUNOSUPPRESSANTS | DAIICHI SANKYO CO LTD (JP) | 2010-07-07 | — | — | EP | claimed |