Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 4/20 | 0.47 |
| ▸ | CSF1R | P07333 | 11/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.46 |
| ▸ | FLT3 | P36888 | 6/20 | 0.46 |
| ▸ | MET | P08581 | 6/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.41 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.41 |
| ▸ | GRK7 | Q8WTQ7 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31352511 | 0.93 | KDR (0.46) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352664 | 0.92 | CSF1R (0.53) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352649 | 0.91 | CSF1R (0.44) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352609 | 0.90 | GRK2 (0.48) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352598 | 0.90 | CSF1R (0.46) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352602 | 0.89 | GRK2 (0.54) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352542 | 0.88 | GRK2 (0.52) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352629 | 0.88 | GRK2 (0.48) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352500 | 0.88 | GRK2 (0.48) | GRK2CSF1RPDGFRAFLT3MET | |
| SCHEMBL31352532 | 0.88 | KDR (0.47) | GRK2CSF1RPDGFRAFLT3MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021943-A1 | QUINAZOLINONE, BENZOXAZINONE AND BENZOXAZEPINONE DERIVATIVES AS PROTEIN KINASE INHIBITORS | NEURALIS (BE) | 2025-01-30 | — | — | WO | disclosed |