Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.48 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956955 | 0.77 | MAP2K1 (0.51) | MAP2K1MAP2K2PRKCZIARS2NUDT1 | |
| SCHEMBL31354782 | 0.76 | MAP2K1 (0.48) | MAP2K1MAP2K2PRKCZIARS2NUDT1 | |
| SCHEMBL31354759 | 0.76 | MAP2K1 (0.62) | MAP2K1MAP2K2PRKCZIARS2NUDT1 | |
| SCHEMBL31354769 | 0.76 | MAP2K1 (0.56) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL29682048 | 0.75 | MAP2K1 (0.64) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL1488238 | 0.75 | MAP2K1 (0.64) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL29413415 | 0.75 | MAP2K1 (0.64) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL29781369 | 0.74 | MAP2K1 (0.60) | MAP2K1MAP2K2PRKCZIARS2NUDT1 | |
| SCHEMBL3885464 | 0.74 | MAP2K1 (0.60) | MAP2K1MAP2K2PRKCZIARS2NUDT1 | |
| SCHEMBL25378942 | 0.74 | MAP2K1 (0.51) | MAP2K1MAP2K2PRKCZIARS2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054260-A1 | INHIBITORS OF MEK KINASE | KINNATE BIOPHARMA INC. (US) | 2025-03-13 | — | — | WO | disclosed |