Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.55 |
| ▸ | MAP2K2 | P36507 | 12/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31354772 | 0.90 | MAP2K1 (0.56) | MAP2K1MAP2K2CA2 | |
| SCHEMBL31354753 | 0.84 | MAP2K1 (0.43) | MAP2K1MAP2K2IDO1CA2BRAF | |
| SCHEMBL31354762 | 0.81 | MAP2K1 (0.67) | MAP2K1MAP2K2IDO1CA2 | |
| SCHEMBL24539656 | 0.78 | MAP2K1 (0.64) | MAP2K1MAP2K2IDO1MAPK1 | |
| SCHEMBL29681825 | 0.78 | MAP2K1 (0.64) | MAP2K1MAP2K2IDO1MAPK1 | |
| SCHEMBL1340491 | 0.74 | MAP2K1 (0.57) | MAP2K1MAP2K2IDO1CA2 | |
| SCHEMBL31354786 | 0.73 | MAP2K1 (0.53) | MAP2K1MAP2K2IDO1CA2 | |
| SCHEMBL31354741 | 0.73 | MAP2K1 (0.58) | MAP2K1MAP2K2CA2BRAFMAPK1 | |
| SCHEMBL31354748 | 0.73 | MAP2K1 (0.67) | MAP2K1MAP2K2CA2 | |
| SCHEMBL2953672 | 0.73 | MAP2K1 (0.67) | MAP2K1MAP2K2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054260-A1 | INHIBITORS OF MEK KINASE | KINNATE BIOPHARMA INC. (US) | 2025-03-13 | — | — | WO | disclosed |