Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185014 | 0.82 | CNR1 (0.41) | KAT6AERN1 | |
| SCHEMBL3096321 | 0.80 | POLB (0.47) | POLBCASP6BRD4SCN9A | |
| SCHEMBL31185005 | 0.80 | POLB (0.41) | POLBCASP6BRD4 | |
| SCHEMBL31184962 | 0.76 | POLB (0.40) | POLBCASP6BRD4 | |
| SCHEMBL3088897 | 0.75 | POLB (0.52) | POLBCASP6BRD4AKR1B10MAPT | |
| SCHEMBL31184689 | 0.75 | CNR1 (0.40) | BRD4ERN1CSNK2A2CLK1CSNK2B | |
| SCHEMBL5478134 | 0.74 | POLB (0.41) | POLBCASP6BRD4AKR1B1 | |
| SCHEMBL3096324 | 0.74 | POLB (0.48) | POLBCASP6BRD4 | |
| SCHEMBL31184813 | 0.73 | POLB (0.40) | POLBCASP6BRD4 | |
| SCHEMBL31355602 | 0.72 | BRD4 (0.36) | POLBCASP6BRD4SCN9AAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330941-A | Antitumor compounds as UPR agonists and uses thereof | 南京圣和药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |