SCHEMBL31355666

SCHEMBL31355666

COC(=O)c1cc(C(F)F)c(Br)c(F)c1NC(=O)NC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29810959 0.86 SOS1 (0.40) SOS1
SCHEMBL24616284 0.86 SOS1 (0.36) SOS1
SCHEMBL26967301 0.86 SOS1 (0.33) SOS1
SCHEMBL26967305 0.84 KDM4E (0.40) SOS1
SCHEMBL24917968 0.83 SOS1 (0.39) SOS1
SCHEMBL29810906 0.83 SOS1 (0.39) SOS1
SCHEMBL24616175 0.81 SOS1 (0.36) SOS1
SCHEMBL31355624 0.81 SOS1 (0.33) SOS1
SCHEMBL31551995 0.78 SOS1 (0.33) SOS1
SCHEMBL25307834 0.78 SOS1 (0.37) SOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025051242-A1 RAS INHIBITOR 泰励生物科技(上海)有限公司 2025-03-13 WO disclosed