SCHEMBL31355841

SCHEMBL31355841

O=C1CCC(c2coc3ccc(NCc4ccc(CNC56CC7CC(CC(C7)C5)C6)cc4)cc23)C(=O)N1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 10/20 0.38
▸ CRBN Q96SW2 10/20 0.38
▸ HDAC6 Q9UBN7 2/20 0.36
▸ GSPT1 P15170 2/20 0.35
▸ CNR2 P34972 1/20 0.34
▸ HDAC1 Q13547 1/20 0.32
▸ HDAC8 Q9BY41 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355879 0.93 DDB1 (0.36) DDB1CRBNHDAC6GSPT1
SCHEMBL31356277 0.88 HDAC6 (0.45) DDB1CRBNHDAC6GSPT1HDAC1
SCHEMBL31356186 0.87 CRBN (0.36) DDB1CRBN
SCHEMBL31356204 0.86 CRBN (0.36) DDB1CRBN
SCHEMBL31356086 0.85 DDB1 (0.31) DDB1CRBN
SCHEMBL31356211 0.81 DDB1 (0.34) DDB1CRBN
SCHEMBL31356215 0.81 DDB1 (0.44) DDB1CRBNGSPT1
SCHEMBL31356045 0.81 CRBN (0.36) DDB1CRBNHDAC6GSPT1
SCHEMBL31355904 0.80 CRBN (0.47) DDB1CRBNHDAC6GSPT1CNR2
SCHEMBL31355813 0.79 DDB1 (0.46) DDB1CRBNHDAC6GSPT1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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