SCHEMBL3135874

SCHEMBL3135874

CCNc1ccc(C(=O)O)c(C)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 2/20 0.49
GAA P10253 1/20 0.49
THRB P10828 1/20 0.49
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
GFER P55789 1/20 0.49
PLEC Q15149 1/20 0.49
FABP4 P15090 1/20 0.46
HCAR3 P49019 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
PKM P14618 2/20 0.42
MAPK1 P28482 1/20 0.42
KDM4C Q9H3R0 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM6B O15054 2/20 0.39
CYP3A4 P08684 2/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13073788 0.85 NPC1 (0.53) KDM4EMAPTALDH1A1HPGDFABP4
SCHEMBL29033346 0.82 KDM6B (0.57) HPGDHCAR3KDM4CKDM6BCYP2C9
SCHEMBL27736211 0.81 KDM6B (0.52) HCAR3KDM4CKDM6BPLK1
SCHEMBL27756887 0.80 PLK1 (0.52) HCAR3KDM4CKDM6BPLK1
SCHEMBL128319 0.78 CYP1A2 (0.58) KDM4EALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL31389208 0.78 CYP1A2 (0.58) KDM4EALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL5386530 0.78 PLK1 (0.58) KDM4EMAPTALDH1A1GAATHRB
SCHEMBL13921284 0.78 MEN1 (0.54) KDM4EMAPTALDH1A1GAATHRB
SCHEMBL28193724 0.77 IDO1 (0.59) KDM4EMAPTALDH1A1GAATHRB
Ammonia Solution, Strong SCHEMBL29137499 0.76 CYP1A2 (0.55) KDM4EALDH1A1HPGDSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1716204-B1 UNSATURATED POLYESTER RESINS OR VINYL ESTER RESIN COMPOSITIONS DSM IP ASSETS BV (NL) 2010-01-27 EP disclosed
EP-1716204-A1 UNSATURATED POLYESTER RESINS OR VINYL ESTER RESIN COMPOSITIONS DSMIP Assets B.V. (NL) 2006-11-02 EP disclosed
WO-2005078020-A1 UNSATURATED POLYESTER RESINS OR VINYL RESIN COMPOSITIONS DSM IP ASSETS B.V. (NL) 2005-08-25 WO disclosed
EP-1564254-A1 Unsaturated polyester resing or vinyl ester resin compositions DSM IP Assets B.V. (NL) 2005-08-17 EP disclosed