Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361122 | 1.00 | KDM4E (0.32) | KDM4E | |
| SCHEMBL31361140 | 1.00 | KDM4E (0.32) | KDM4E | |
| SCHEMBL31361164 | 1.00 | KDM4E (0.32) | KDM4E | |
| SCHEMBL31361188 | 0.88 | KDM4E (0.32) | KDM4E | |
| SCHEMBL31361183 | 0.87 | KDM4E (0.30) | KDM4E | |
| SCHEMBL31361231 | 0.87 | KDM4E (0.30) | KDM4E | |
| SCHEMBL31361197 | 0.87 | KDM4E (0.30) | KDM4E | |
| SCHEMBL31361185 | 0.87 | KDM4E (0.30) | KDM4E | |
| SCHEMBL31361159 | 0.81 | KDM4E (0.33) | KDM4E | |
| SCHEMBL31361224 | 0.81 | KDM4E (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746965-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017041-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |