Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361254 | 0.90 | PDE5A (0.46) | CACNA2D1CCNE2CCNE1CDK2EGFR | |
| SCHEMBL31361280 | 0.81 | CACNA2D1 (0.51) | CACNA2D1CCNE2CCNE1CDK2EGFR | |
| SCHEMBL31361255 | 0.72 | CACNA2D1 (0.43) | CACNA2D1CCNE2CCNE1CDK2EGFR | |
| SCHEMBL31361287 | 0.70 | CYP1A2 (0.36) | POLBPDE5AMEN1KMT2AHTT | |
| SCHEMBL3758745 | 0.66 | EGFR (0.67) | EGFRPOLBNR2F2HTTLMNA | |
| SCHEMBL5004454 | 0.65 | CACNA2D1 (1.00) | CACNA2D1 | |
| SCHEMBL28693946 | 0.65 | HPGD (0.67) | EGFRPOLBNR2F2MEN1KMT2A | |
| SCHEMBL28672895 | 0.64 | HPGD (0.66) | EGFRPOLBNR2F2MEN1KMT2A | |
| SCHEMBL3118629 | 0.64 | APP (0.68) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL28679824 | 0.64 | HPGD (0.62) | EGFRPOLBNR2F2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161346-A | Pyrrolo-ring compound and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2024-12-20 | — | — | CN | disclosed |